Cargando…
Integrative multi-omic analysis identifies new drivers and pathways in molecularly distinct subtypes of ALS
Amyotrophic lateral sclerosis (ALS) is an incurable and fatal neurodegenerative disease. Increasing the chances of success for future clinical strategies requires more in-depth knowledge of the molecular basis underlying disease heterogeneity. We recently laid the foundation for a molecular taxonomy...
Autores principales: | Morello, Giovanna, Guarnaccia, Maria, Spampinato, Antonio Gianmaria, Salomone, Salvatore, D’Agata, Velia, Conforti, Francesca Luisa, Aronica, Eleonora, Cavallaro, Sebastiano |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620285/ https://www.ncbi.nlm.nih.gov/pubmed/31292500 http://dx.doi.org/10.1038/s41598-019-46355-w |
Ejemplares similares
-
From Multi-Omics Approaches to Precision Medicine in Amyotrophic Lateral Sclerosis
por: Morello, Giovanna, et al.
Publicado: (2020) -
Selection and Prioritization of Candidate Drug Targets for Amyotrophic Lateral Sclerosis Through a Meta-Analysis Approach
por: Morello, Giovanna, et al.
Publicado: (2017) -
Copy Number Variations in Amyotrophic Lateral Sclerosis: Piecing the Mosaic Tiles Together through a Systems Biology Approach
por: Morello, Giovanna, et al.
Publicado: (2017) -
Transcriptional Profiles of Cell Fate Transitions Reveal Early Drivers of Neuronal Apoptosis and Survival
por: Morello, Giovanna, et al.
Publicado: (2021) -
CXCR2 Is Deregulated in ALS Spinal Cord and Its Activation Triggers Apoptosis in Motor Neuron-Like Cells Overexpressing hSOD1-G93A
por: La Cognata, Valentina, et al.
Publicado: (2023)