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Anti-cancer activity of the novel 2-hydroxydiarylamide derivatives IMD-0354 and KRT1853 through suppression of cancer cell invasion, proliferation, and survival mediated by TMPRSS4

Elevated expression of transmembrane serine protease 4 (TMPRSS4) correlates with poor prognosis in non-small cell lung cancer, gastric cancer, colorectal cancer, prostate cancer, and other cancer patients. Previously, we demonstrated that TMPRSS4 mediates tumor cell invasion, migration, proliferatio...

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Detalles Bibliográficos
Autores principales: Kim, Solbi, Ko, Dongjoon, Lee, Yunhee, Jang, Seonghui, Lee, Younghoon, Lee, Ill Young, Kim, Semi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620293/
https://www.ncbi.nlm.nih.gov/pubmed/31292507
http://dx.doi.org/10.1038/s41598-019-46447-7