The astrocyte transcriptome in EAE optic neuritis shows complement activation and reveals a sex difference in astrocytic C3 expression

Multiple sclerosis (MS) is a neuroinflammatory multifocal disorder. Optic neuritis is common in MS and leads to visual disability. No current treatments repair this damage. Discerning gene expression changes within specific cell types in optic nerve (ON) may suggest new treatment targets for visual...

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Detalles Bibliográficos
Autores principales: Tassoni, Alessia, Farkhondeh, Vista, Itoh, Yuichiro, Itoh, Noriko, Sofroniew, Michael V., Voskuhl, Rhonda R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620300/
https://www.ncbi.nlm.nih.gov/pubmed/31292459
http://dx.doi.org/10.1038/s41598-019-46232-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620300/
https://www.ncbi.nlm.nih.gov/pubmed/31292459
http://dx.doi.org/10.1038/s41598-019-46232-6

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