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HIV-1 tropism prediction by the XGboost and HMM methods

Human Immunodeficiency Virus 1 (HIV-1) co-receptor usage, called tropism, is associated with disease progression towards AIDS. Furthermore, the recently developed and developing drugs against co-receptors CCR5 or CXCR4 open a new thought for HIV-1 therapy. Thus, knowledge about tropism is critical f...

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Detalles Bibliográficos
Autores principales: Chen, Xiang, Wang, Zhi-Xin, Pan, Xian-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620319/
https://www.ncbi.nlm.nih.gov/pubmed/31292462
http://dx.doi.org/10.1038/s41598-019-46420-4