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MicroRNA-221 promotes cisplatin resistance in osteosarcoma cells by targeting PPP2R2A

Osteosarcoma (OS), the most common malignant bone tumor, is the main cause of cancer-related deaths in children and young adults. Despite the combination of surgery and multi-agent chemotherapy, patients with OS who develop resistance to chemotherapy or experience recurrence have a dismal prognosis....

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Detalles Bibliográficos
Autores principales: Yu, Wen-chao, Chen, Hui-hao, Qu, Yan-yan, Xu, Chun-wei, Yang, Chen, Liu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620383/
https://www.ncbi.nlm.nih.gov/pubmed/31221814
http://dx.doi.org/10.1042/BSR20190198