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Gram-scale synthesis of FICZ, a photoreactive endogenous ligand of the aryl hydrocarbon receptor
Development of an efficient and scalable synthesis of 6-formylindolo[3,2-b]carbazole (FICZ), a naturally-occurring aryl hydrocarbon receptor (AhR) ligand, allowed its biological and physical properties to be studied. FICZ was shown to be the most potent among a series of 6-substituted indolo[3,2-b]c...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620467/ https://www.ncbi.nlm.nih.gov/pubmed/31292477 http://dx.doi.org/10.1038/s41598-019-46374-7 |