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3D Reconstruction of the Neurovascular Unit Reveals Differential Loss of Cholinergic Innervation in the Cortex and Hippocampus of the Adult Mouse Brain

Increasing evidence supports a role for cerebrovasculature dysfunction in the etiology of Alzheimer’s disease (AD). Blood vessels in the brain are composed of a collection of cells and acellular material that comprise the neurovascular unit (NVU). The NVU in the hippocampus and cortex receives inner...

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Detalles Bibliográficos
Autores principales: Nizari, Shereen, Carare, Roxana O., Romero, Ignacio A., Hawkes, Cheryl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620643/
https://www.ncbi.nlm.nih.gov/pubmed/31333445
http://dx.doi.org/10.3389/fnagi.2019.00172