Self-assembled insulin and nanogels polyelectrolyte complex (Ins/NGs-PEC) for oral insulin delivery: characterization, lyophilization and in-vivo evaluation

Introduction: Insulin is given by injection, because when administered orally, it would be destroyed by enzymes in the digestive system, hence only about 0.1% reaches blood circulation. The purpose of the present study was to use pH sensitive polyelectrolyte methyl methacrylate (MMA)/itaconic acid (...

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Detalles Bibliográficos
Autores principales: Mudassir, Jahanzeb, Darwis, Yusrida, Muhamad, Suriani, Khan, Arshad Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620829/
https://www.ncbi.nlm.nih.gov/pubmed/31456636
http://dx.doi.org/10.2147/IJN.S199507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620829/
https://www.ncbi.nlm.nih.gov/pubmed/31456636
http://dx.doi.org/10.2147/IJN.S199507

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