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Folic Acid Receptor-Mediated Targeting Enhances the Cytotoxicity, Efficacy, and Selectivity of Withania somnifera Leaf Extract: In vitro and in vivo Evidence

Nanomedicine holds great potential for drug delivery to achieve more effective and safer cancer treatment. Earlier, we reported that the alcoholic extract of Withania somnifera leaves (i-Extract) has selective cancer cell killing activity. Herein, we developed a folate receptor-targeting i-Extract n...

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Detalles Bibliográficos
Autores principales: Yu, Yue, Wang, Jia, Kaul, Sunil C., Wadhwa, Renu, Miyako, Eijiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621239/
https://www.ncbi.nlm.nih.gov/pubmed/31334122
http://dx.doi.org/10.3389/fonc.2019.00602