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Route of Vaccine Administration Influences the Impact of Fms-Like Tyrosine Kinase 3 Ligand (Flt3L) on Chlamydial-Specific Protective Immune Responses

We tested the hypothesis that the impact of the Fms-like tyrosine kinase 3-ligand (Flt3L; FL) on recombinant Vibrio cholerae ghost (rVCG) vaccine-induced chlamydial immunity is influenced by route of vaccine delivery. Female C57BL/6J mice were immunized rectally (IR) or intramuscularly (IM) with rVC...

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Detalles Bibliográficos
Autores principales: Pais, Roshan, Omosun, Yusuf, Igietseme, Joseph U., Fujihashi, Kohtaro, Eko, Francis O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621642/
https://www.ncbi.nlm.nih.gov/pubmed/31333682
http://dx.doi.org/10.3389/fimmu.2019.01577