Oncolytic adenovirus drives specific immune response generated by a poly-epitope pDNA vaccine encoding melanoma neoantigens into the tumor site

BACKGROUND: DNA vaccines against cancer held great promises due to the generation of a specific and long-lasting immune response. However, when used as a single therapy, they are not able to drive the generated immune response into the tumor, because of the immunosuppressive microenvironment, thus l...

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Detalles Bibliográficos
Autores principales: Lopes, Alessandra, Feola, Sara, Ligot, Sophie, Fusciello, Manlio, Vandermeulen, Gaëlle, Préat, Véronique, Cerullo, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621971/
https://www.ncbi.nlm.nih.gov/pubmed/31291991
http://dx.doi.org/10.1186/s40425-019-0644-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621971/
https://www.ncbi.nlm.nih.gov/pubmed/31291991
http://dx.doi.org/10.1186/s40425-019-0644-7

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