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Role of antibiotic use, plasma citrulline and blood microbiome in advanced non-small cell lung cancer patients treated with nivolumab

BACKGROUND: Recent data suggested a role of gut microbiota and antibiotic use on immune checkpoint inhibitors efficacy. We aimed to evaluate the impact of early use of antibiotic (EUA), blood microbiome and plasmatic citrulline (marker of the intestinal barrier) on nivolumab efficacy in non-small ce...

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Detalles Bibliográficos
Autores principales: Ouaknine Krief, Julia, Helly de Tauriers, Pierre, Dumenil, Coraline, Neveux, Nathalie, Dumoulin, Jennifer, Giraud, Violaine, Labrune, Sylvie, Tisserand, Julie, Julie, Catherine, Emile, Jean-François, Chinet, Thierry, Giroux Leprieur, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621972/
https://www.ncbi.nlm.nih.gov/pubmed/31292005
http://dx.doi.org/10.1186/s40425-019-0658-1