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Influence of DNMT3A R882 mutations on AML prognosis determined by the allele ratio in Chinese patients
BACKGROUND: The influence of DNMT3A R882 mutations on adult acute myeloid leukemia (AML) prognosis is still controversial presently. The influence of R882 allele ratio on drug response and prognosis of AML is unknown yet. Besides, it is obscure whether anthracyclines are involved in chemoresistance...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621981/ https://www.ncbi.nlm.nih.gov/pubmed/31291961 http://dx.doi.org/10.1186/s12967-019-1959-3 |