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Influence of DNMT3A R882 mutations on AML prognosis determined by the allele ratio in Chinese patients

BACKGROUND: The influence of DNMT3A R882 mutations on adult acute myeloid leukemia (AML) prognosis is still controversial presently. The influence of R882 allele ratio on drug response and prognosis of AML is unknown yet. Besides, it is obscure whether anthracyclines are involved in chemoresistance...

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Detalles Bibliográficos
Autores principales:	Yuan, Xiao-Qing, Chen, Peng, Du, Yin-Xiao, Zhu, Ke-Wei, Zhang, Dao-Yu, Yan, Han, Liu, Han, Liu, Yan-Ling, Cao, Shan, Zhou, Gan, Zeng, Hui, Chen, Shu-Ping, Zhao, Xie-Lan, Yang, Jing, Zeng, Wen-Jing, Chen, Xiao-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621981/ https://www.ncbi.nlm.nih.gov/pubmed/31291961 http://dx.doi.org/10.1186/s12967-019-1959-3

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