Evolutionary couplings detect side-chain interactions

Patterns of amino acid covariation in large protein sequence alignments can inform the prediction of de novo protein structures, binding interfaces, and mutational effects. While algorithms that detect these so-called evolutionary couplings between residues have proven useful for practical applicati...

Descripción completa

Detalles Bibliográficos
Autores principales: Hockenberry, Adam J., Wilke, Claus O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6622159/
https://www.ncbi.nlm.nih.gov/pubmed/31328041
http://dx.doi.org/10.7717/peerj.7280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6622159/
https://www.ncbi.nlm.nih.gov/pubmed/31328041
http://dx.doi.org/10.7717/peerj.7280

Ejemplares similares