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Structural and evolutionary characteristics of dynamin-related GTPase OPA1

OPA1 is a dynamin-related GTPase that controls mitochondrial fusion, cristae remodeling, energetics and mtDNA maintenance. However, the molecular architecture of OPA1 is poorly understood. Here we modeled the structure of human OPA1 by the threading approach. We found that the C-terminal region of t...

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Detalles Bibliográficos
Autores principales: Li, Dandan, Wang, Jinlan, Jin, Zichen, Zhang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6622160/
https://www.ncbi.nlm.nih.gov/pubmed/31328044
http://dx.doi.org/10.7717/peerj.7285