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A20 in dendritic cells restrains intestinal anti-bacterial peptide expression and preserves commensal homeostasis

Microbial dysbiosis commonly occurs in patients with inflammatory bowel diseases (IBD). Exogenous causes of dysbiosis such as antibiotics and diet are well described, but host derived causes are understudied. A20 is a potent regulator of signals triggered by microbial pattern molecules, and A20 regu...

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Detalles Bibliográficos
Autores principales: Talpin, Alice, Kattah, Michael G., Advincula, Rommel, Fadrosh, Douglas, Lynch, Kole, LaMere, Brandon, Fujimura, Kei E., Nagalingam, Nabeetha A., Malynn, Barbara A., Lynch, Susan V., Ma, Averil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6622485/
https://www.ncbi.nlm.nih.gov/pubmed/31295268
http://dx.doi.org/10.1371/journal.pone.0218999