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Reproduction disrupts stem cell homeostasis in testes of aged male Drosophila via an induced microenvironment
Stem cells rely on instructive cues from their environment. Alterations in microenvironments might contribute to tissue dysfunction and disease pathogenesis. Germline stem cells (GSCs) and cyst stem cells (CySC) in Drosophila testes are normally maintained in the apical area by the testicular hub. I...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6622487/ https://www.ncbi.nlm.nih.gov/pubmed/31295251 http://dx.doi.org/10.1371/journal.pgen.1008062 |