Reproduction disrupts stem cell homeostasis in testes of aged male Drosophila via an induced microenvironment

Stem cells rely on instructive cues from their environment. Alterations in microenvironments might contribute to tissue dysfunction and disease pathogenesis. Germline stem cells (GSCs) and cyst stem cells (CySC) in Drosophila testes are normally maintained in the apical area by the testicular hub. I...

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Detalles Bibliográficos
Autores principales: Chang, Yi Chieh, Tu, Hsin, Chen, Jing-Yi, Chang, Ching-Chin, Yang, Shu Yuan, Pi, Haiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6622487/
https://www.ncbi.nlm.nih.gov/pubmed/31295251
http://dx.doi.org/10.1371/journal.pgen.1008062

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