Hepatocellular heme oxygenase 1 deficiency does not affect inflammatory hepcidin regulation in mice

Hepcidin is an iron regulatory peptide hormone that is secreted from hepatocytes and inhibits iron efflux from tissues to plasma. Under inflammatory conditions, hepcidin is transcriptionally induced by IL-6/STAT3 signaling and promotes hypoferremia, an innate immune response to infection. If this pa...

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Detalles Bibliográficos
Autores principales: Charlebois, Edouard, Fillebeen, Carine, Pantopoulos, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6623421/
https://www.ncbi.nlm.nih.gov/pubmed/31295319
http://dx.doi.org/10.1371/journal.pone.0219835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6623421/
https://www.ncbi.nlm.nih.gov/pubmed/31295319
http://dx.doi.org/10.1371/journal.pone.0219835

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