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Topological integration of RPPA proteomic data with multi-omics data for survival prediction in breast cancer via pathway activity inference

BACKGROUND: The analysis of integrated multi-omics data enables the identification of disease-related biomarkers that cannot be identified from a single omics profile. Although protein-level data reflects the cellular status of cancer tissue more directly than gene-level data, past studies have main...

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Detalles Bibliográficos
Autores principales: Kim, Tae Rim, Jeong, Hyun-Hwan, Sohn, Kyung-Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624183/
https://www.ncbi.nlm.nih.gov/pubmed/31296204
http://dx.doi.org/10.1186/s12920-019-0511-x