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Topological integration of RPPA proteomic data with multi-omics data for survival prediction in breast cancer via pathway activity inference
BACKGROUND: The analysis of integrated multi-omics data enables the identification of disease-related biomarkers that cannot be identified from a single omics profile. Although protein-level data reflects the cellular status of cancer tissue more directly than gene-level data, past studies have main...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624183/ https://www.ncbi.nlm.nih.gov/pubmed/31296204 http://dx.doi.org/10.1186/s12920-019-0511-x |