Regulation of tumor angiogenesis and mesenchymal–endothelial transition by p38α through TGF-β and JNK signaling

The formation of new blood vessels is essential for normal development, tissue repair and tumor growth. Here we show that inhibition of the kinase p38α enhances angiogenesis in human and mouse colon tumors. Mesenchymal cells can contribute to tumor angiogenesis by regulating proliferation and migrat...

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Detalles Bibliográficos
Autores principales: Batlle, Raquel, Andrés, Eva, Gonzalez, Lorena, Llonch, Elisabet, Igea, Ana, Gutierrez-Prat, Núria, Berenguer-Llergo, Antoni, Nebreda, Angel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624205/
https://www.ncbi.nlm.nih.gov/pubmed/31296856
http://dx.doi.org/10.1038/s41467-019-10946-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624205/
https://www.ncbi.nlm.nih.gov/pubmed/31296856
http://dx.doi.org/10.1038/s41467-019-10946-y

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