cPLA2 activation contributes to lysosomal defects leading to impairment of autophagy after spinal cord injury

The autophagy–lysosomal pathway plays an essential role in cellular homeostasis as well as a protective function against a variety of diseases including neurodegeneration. Conversely, inhibition of autophagy, for example due to lysosomal dysfunction, can lead to pathological accumulation of dysfunct...

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Detalles Bibliográficos
Autores principales: Li, Yun, Jones, Jace W., M. C. Choi, Harry, Sarkar, Chinmoy, Kane, Maureen A., Koh, Eugene Y., Lipinski, Marta M., Wu, Junfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624263/
https://www.ncbi.nlm.nih.gov/pubmed/31296844
http://dx.doi.org/10.1038/s41419-019-1764-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624263/
https://www.ncbi.nlm.nih.gov/pubmed/31296844
http://dx.doi.org/10.1038/s41419-019-1764-1

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