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High Fat Diet Triggers a Reduction in Body Fat Mass in Female Mice Deficient for Utx demethylase

Obesity increases the risk of metabolic disorders like diabetes mellitus and dyslipidemia. However, how metabolic status is sensed and regulates cellular behavior is unclear. Utx is an H3K27 demethylase that influences adipocyte function in vitro. To examine its role in vivo, we generated mice lacki...

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Detalles Bibliográficos
Autores principales: Ota, Kazushige, Komuro, Akiyoshi, Amano, Hisayuki, Kanai, Akinori, Ge, Kai, Ueda, Takeshi, Okada, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624269/
https://www.ncbi.nlm.nih.gov/pubmed/31296899
http://dx.doi.org/10.1038/s41598-019-46445-9