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High Fat Diet Triggers a Reduction in Body Fat Mass in Female Mice Deficient for Utx demethylase
Obesity increases the risk of metabolic disorders like diabetes mellitus and dyslipidemia. However, how metabolic status is sensed and regulates cellular behavior is unclear. Utx is an H3K27 demethylase that influences adipocyte function in vitro. To examine its role in vivo, we generated mice lacki...
Autores principales: | Ota, Kazushige, Komuro, Akiyoshi, Amano, Hisayuki, Kanai, Akinori, Ge, Kai, Ueda, Takeshi, Okada, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624269/ https://www.ncbi.nlm.nih.gov/pubmed/31296899 http://dx.doi.org/10.1038/s41598-019-46445-9 |
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