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A nanoscale, multi-parametric flow cytometry-based platform to study mitochondrial heterogeneity and mitochondrial DNA dynamics

Mitochondria are well-characterized regarding their function in both energy production and regulation of cell death; however, the heterogeneity that exists within mitochondrial populations is poorly understood. Typically analyzed as pooled samples comprised of millions of individual mitochondria, th...

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Detalles Bibliográficos
Autores principales: MacDonald, Julie A., Bothun, Alisha M., Annis, Sofia N., Sheehan, Hannah, Ray, Somak, Gao, Yuanwei, Ivanov, Alexander R., Khrapko, Konstantin, Tilly, Jonathan L., Woods, Dori C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624292/
https://www.ncbi.nlm.nih.gov/pubmed/31312727
http://dx.doi.org/10.1038/s42003-019-0513-4