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A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression

Adolescent idiopathic scoliosis is the most prevalent spine deformity and the molecular mechanisms underlying its pathophysiology remain poorly understood. We have previously found a differential impairment of melatonin receptor signaling in AIS osteoblasts allowing the classification of patients in...

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Detalles Bibliográficos
Autores principales: Akoume, Marie-Yvonne, Elbakry, Mohamed, Veillette, Maxime, Franco, Anita, Nada, Dina, Labelle, Hubert, Mac-Thiong, Jean-Marc, Grimard, Guy, Ouellet, Jean, Parent, Stefan, Rivard, Charles-Hilaire, Lombardi, Giovanni, Colombini, Alessandra, Banfi, Giuseppe, Brayda-Bruno, Marco, Gorman, Kristen F., Moreau, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624302/
https://www.ncbi.nlm.nih.gov/pubmed/31296888
http://dx.doi.org/10.1038/s41598-019-46325-2