The Cajal Body Protein WRAP53β Prepares the Scene for Repair of DNA Double-Strand Breaks by Regulating Local Ubiquitination

Proper repair of DNA double-strand breaks is critical for maintaining genome integrity and avoiding disease. Modification of damaged chromatin has profound consequences for the initial signaling and regulation of repair. One such modification involves ubiquitination by E3 ligases RNF8 and RNF168 wit...

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Detalles Bibliográficos
Autores principales: Bergstrand, Sofie, O'Brien, Eleanor M., Farnebo, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624377/
https://www.ncbi.nlm.nih.gov/pubmed/31334247
http://dx.doi.org/10.3389/fmolb.2019.00051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624377/
https://www.ncbi.nlm.nih.gov/pubmed/31334247
http://dx.doi.org/10.3389/fmolb.2019.00051

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