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Population pharmacokinetics of immediate‐ and prolonged‐release tacrolimus formulations in liver, kidney and heart transplant recipients

AIMS: Develop a population pharmacokinetics model of tacrolimus in organ transplant recipients receiving twice‐daily, immediate‐release (IR‐T; Prograf) and/or once‐daily, prolonged‐release (PR‐T; Advagraf or Astagraf XL) tacrolimus. METHODS: Tacrolimus concentration–time profiles were analysed from...

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Detalles Bibliográficos
Autores principales: Lu, Zheng, Bonate, Peter, Keirns, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624387/
https://www.ncbi.nlm.nih.gov/pubmed/30950096
http://dx.doi.org/10.1111/bcp.13952