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Methadone and buprenorphine pharmacokinetics and pharmacodynamics when coadministered with fostemsavir to opioid‐dependent, human immunodeficiency virus seronegative participants

AIMS: Regional human immunodeficiency virus (HIV) prevalence rates are high in people with history of injection drug use, including those managed with maintenance opioids. Fostemsavir (FTR) is an oral prodrug of temsavir, a first‐in‐class attachment inhibitor that binds HIV‐1 gp120, preventing initi...

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Detalles Bibliográficos
Autores principales: Moore, Katy, Magee, Mindy, Sevinsky, Heather, Chang, Ming, Lubin, Susan, Myers, Elsa, Ackerman, Peter, Llamoso, Cyril
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624406/
https://www.ncbi.nlm.nih.gov/pubmed/30980734
http://dx.doi.org/10.1111/bcp.13964