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Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1

Protein:protein interactions are the basis of molecular communication and are usually of transient non-covalent nature, while covalent interactions other than ubiquitination are rare. For cellular adaptations, the cellular oxygen and peroxide sensor factor inhibiting HIF (FIH) confers oxygen and oxi...

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Detalles Bibliográficos
Autores principales: Pickel, Christina, Günter, Julia, Ruiz-Serrano, Amalia, Spielmann, Patrick, Fabrizio, Jacqueline-Alba, Wolski, Witold, Peet, Daniel J., Wenger, Roland H., Scholz, Carsten C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624438/
https://www.ncbi.nlm.nih.gov/pubmed/31299612
http://dx.doi.org/10.1016/j.redox.2019.101265