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Baseline T cell dysfunction by single cell network profiling in metastatic breast cancer patients

BACKGROUND: We previously reported the results of a multicentric prospective randomized trial of chemo-refractory metastatic breast cancer patients testing the efficacy of two doses of TGFβ blockade during radiotherapy. Despite a lack of objective responses to the combination, patients who received...

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Detalles Bibliográficos
Autores principales: Formenti, Silvia C., Hawtin, Rachael E., Dixit, Neha, Evensen, Erik, Lee, Percy, Goldberg, Judith D., Li, Xiaochun, Vanpouille-Box, Claire, Schaue, Dörthe, McBride, William H., Demaria, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624899/
https://www.ncbi.nlm.nih.gov/pubmed/31296256
http://dx.doi.org/10.1186/s40425-019-0633-x