The endonuclease APE1 processes miR-92b formation, thereby regulating expression of the tumor suppressor LDLR in cervical cancer cells

BACKGROUND: The molecular mechanisms underlying cervical cancer require elucidation to identify novel therapeutic targets. Apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) is a multifunctional apurinic/apyrimidinic (AP) endonuclease that influences the transcription of many cancer-related genes...

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Detalles Bibliográficos
Autores principales: Sun, Yi, Feng, Yun, Zhang, Guiqian, Xu, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624912/
https://www.ncbi.nlm.nih.gov/pubmed/31320936
http://dx.doi.org/10.1177/1758835919855859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624912/
https://www.ncbi.nlm.nih.gov/pubmed/31320936
http://dx.doi.org/10.1177/1758835919855859

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