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Noncatalytic Function of a JmjC Domain Protein Disrupts Heterochromatin

Chromatin-modifying enzymes are frequently overexpressed in cancer cells, and their enzymatic activities play important roles in changing the epigenetic landscape responsible for tumorigenesis. However, many of these proteins also execute noncatalytic functions, which are poorly understood. In fissi...

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Detalles Bibliográficos
Autores principales: Bao, Kehan, Jia, Songtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624913/
https://www.ncbi.nlm.nih.gov/pubmed/31321383
http://dx.doi.org/10.1177/2516865719862249