Genome-wide mapping and profiling of γH2AX binding hotspots in response to different replication stress inducers

BACKGROUND: Replication stress (RS) gives rise to DNA damage that threatens genome stability. RS can originate from different sources that stall replication by diverse mechanisms. However, the mechanism underlying how different types of RS contribute to genome instability is unclear, in part due to...

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Detalles Bibliográficos
Autores principales: Lyu, Xinxing, Chastain, Megan, Chai, Weihang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625122/
https://www.ncbi.nlm.nih.gov/pubmed/31299901
http://dx.doi.org/10.1186/s12864-019-5934-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625122/
https://www.ncbi.nlm.nih.gov/pubmed/31299901
http://dx.doi.org/10.1186/s12864-019-5934-4

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