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Genome-wide mapping and profiling of γH2AX binding hotspots in response to different replication stress inducers
BACKGROUND: Replication stress (RS) gives rise to DNA damage that threatens genome stability. RS can originate from different sources that stall replication by diverse mechanisms. However, the mechanism underlying how different types of RS contribute to genome instability is unclear, in part due to...
Autores principales: | Lyu, Xinxing, Chastain, Megan, Chai, Weihang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625122/ https://www.ncbi.nlm.nih.gov/pubmed/31299901 http://dx.doi.org/10.1186/s12864-019-5934-4 |
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