Telomerase insufficiency induced telomere erosion accumulation in successive generations in dyskeratosis congenita family

BACKGROUND: Dyskeratosis congenita (DC) is a rare heritable bone marrow failure syndrome that is associated with telomere dysfunction, and has high genetic heterogeneity and varied features. OBJECTIVE: This study aimed to identify the underlying genetic etiology of a DC family with more severe sympt...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Caixia, Jing, Shuang, Dai, Congling, Tu, Chaofeng, Tan, Zhenhua, Du, Juan, Lu, Guang‐Xiu, Lin, Ge, Zeng, Sicong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625126/
https://www.ncbi.nlm.nih.gov/pubmed/31119896
http://dx.doi.org/10.1002/mgg3.709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625126/
https://www.ncbi.nlm.nih.gov/pubmed/31119896
http://dx.doi.org/10.1002/mgg3.709

Ejemplares similares