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Telomerase insufficiency induced telomere erosion accumulation in successive generations in dyskeratosis congenita family
BACKGROUND: Dyskeratosis congenita (DC) is a rare heritable bone marrow failure syndrome that is associated with telomere dysfunction, and has high genetic heterogeneity and varied features. OBJECTIVE: This study aimed to identify the underlying genetic etiology of a DC family with more severe sympt...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625126/ https://www.ncbi.nlm.nih.gov/pubmed/31119896 http://dx.doi.org/10.1002/mgg3.709 |