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Characterization of BRCA1 and BRCA2 genetic variants in a cohort of Bahraini breast cancer patients using next‐generation sequencing

BACKGROUND: Breast cancer is the most common malignancy in women worldwide. About 5%–10% are due to hereditary predisposition. The contribution of BRCA1/2 mutations to familial breast cancer in Bahrain has not been explored. The objective of this study was to investigate the spectrum of BRCA1/2 gene...

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Detalles Bibliográficos
Autores principales: Al Hannan, Fatima, Keogh, Michael B., Taha, Safa, Al Buainain, Latifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625152/
https://www.ncbi.nlm.nih.gov/pubmed/31131559
http://dx.doi.org/10.1002/mgg3.771