Mast Cell/Proteinase Activated Receptor 2 (PAR2) Mediated Interactions in the Pathogenesis of Discogenic Back Pain

Mast cells (MCs) are present in the painful degenerate human intervertebral disc (IVD) and are associated with disease pathogenesis. MCs release granules containing enzymatic and inflammatory factors in response to stimulants or allergens. The serine protease, tryptase, is unique to MCs and its acti...

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Detalles Bibliográficos
Autores principales: Richards, Justin, Tang, Shirley, Gunsch, Gilian, Sul, Pavel, Wiet, Matthew, Flanigan, David C., Khan, Safdar N., Moore, Sarah, Walter, Benjamin, Purmessur, Devina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625229/
https://www.ncbi.nlm.nih.gov/pubmed/31333416
http://dx.doi.org/10.3389/fncel.2019.00294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625229/
https://www.ncbi.nlm.nih.gov/pubmed/31333416
http://dx.doi.org/10.3389/fncel.2019.00294

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