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p53 mediates PEDF-induced autophagy in human umbilical vein endothelial cells through sestrin2 signaling

Autophagy is a conserved catabolic process by which cytoplasmic components are delivered into lysosomes for degradation. Pigment epithelium-derived factor (PEDF) has been reported to be associated with autophagy and can induce p53 expression; however, the mechanism relating PEDF with autophagy in en...

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Detalles Bibliográficos
Autores principales: Chen, Tiangui, Li, Tianbo, Wang, Jiangning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625384/
https://www.ncbi.nlm.nih.gov/pubmed/31173218
http://dx.doi.org/10.3892/mmr.2019.10319