Impaired AMPK-CGRP signaling in the central nervous system contributes to enhanced neuropathic pain in high-fat diet-induced obese rats, with or without nerve injury

Obesity is associated with increased sensitivity to pain, including neuropathic pain, but the precise mechanisms are not fully understood. Recent evidence has revealed that AMP-activated protein kinase (AMPK) in the central nervous system (CNS) regulates the neuropeptide calcitonin gene-related pept...

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Detalles Bibliográficos
Autores principales: Guo, Xinxin, Tao, Xueshu, Tong, Qing, Li, Tiecheng, Dong, Daosong, Zhang, Bohan, Zhao, Mengnan, Song, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625401/
https://www.ncbi.nlm.nih.gov/pubmed/31173269
http://dx.doi.org/10.3892/mmr.2019.10368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625401/
https://www.ncbi.nlm.nih.gov/pubmed/31173269
http://dx.doi.org/10.3892/mmr.2019.10368

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