17β-Estradiol protects against interleukin-1β-induced apoptosis in rat nucleus pulposus cells via the mTOR/caspase-3 pathway

Intervertebral disc degeneration (IVDD) is the main pathological basis of spinal degenerative diseases, and aberrant apoptosis of nucleus pulposus cells (NPCs) is the main cellular process that causes IVDD. In our previous studies, 17β-estradiol (E(2)) was demonstrated to protect rat NPCs from inter...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Hong-Tao, Yang, Si-Dong, Zhang, Feng, Liu, Sen, Yang, Da-Long, Ma, Lei, Wang, Hui, Ding, Wen-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625415/
https://www.ncbi.nlm.nih.gov/pubmed/31257459
http://dx.doi.org/10.3892/mmr.2019.10384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625415/
https://www.ncbi.nlm.nih.gov/pubmed/31257459
http://dx.doi.org/10.3892/mmr.2019.10384

Ejemplares similares