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Pharmacokinetics, excretion and metabolites analysis of DL0410, a dual-acting cholinesterase inhibitor and histamine-3 receptor antagonist

DL0410, a dual-action cholinesterase inhibitor and histamine-3 receptor antagonist with a novel structural scaffold, may be a potential candidate for the treatment of Alzheimer's disease (AD). To the best of the authors' knowledge, this is the first study to demonstrate a reliable method f...

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Detalles Bibliográficos
Autores principales: Pang, Xiaocong, Zhao, Ying, Song, Junke, Kang, De, Wu, Song, Wang, Lin, Liu, Ailin, Du, Guanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625456/
https://www.ncbi.nlm.nih.gov/pubmed/31173186
http://dx.doi.org/10.3892/mmr.2019.10306