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Pharmacokinetic changes and therapeutic drug monitoring of lamotrigine during pregnancy

OBJECTIVES: To evaluate the pharmacokinetic changes in lamotrigine (LTG) from prepregnancy to postpartum and to assess the impact of therapeutic drug monitoring (TDM) on seizure management during pregnancy in a Chinese population. METHODS: A series of women who were on LTG monotherapy before concept...

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Detalles Bibliográficos
Autores principales: Ding, Ye, Tan, Xiaoping, Zhang, Shuo, Guo, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625463/
https://www.ncbi.nlm.nih.gov/pubmed/31104352
http://dx.doi.org/10.1002/brb3.1315