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The invasion of de-differentiating cancer cells into hierarchical tissues
Many fast renewing tissues are characterized by a hierarchical cellular architecture, with tissue specific stem cells at the root of the cellular hierarchy, differentiating into a whole range of specialized cells. There is increasing evidence that tumors are structured in a very similar way, mirrori...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625723/ https://www.ncbi.nlm.nih.gov/pubmed/31260442 http://dx.doi.org/10.1371/journal.pcbi.1007167 |