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DART-ID increases single-cell proteome coverage

Analysis by liquid chromatography and tandem mass spectrometry (LC-MS/MS) can identify and quantify thousands of proteins in microgram-level samples, such as those comprised of thousands of cells. This process, however, remains challenging for smaller samples, such as the proteomes of single mammali...

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Detalles Bibliográficos
Autores principales: Chen, Albert Tian, Franks, Alexander, Slavov, Nikolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625733/
https://www.ncbi.nlm.nih.gov/pubmed/31260443
http://dx.doi.org/10.1371/journal.pcbi.1007082