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DART-ID increases single-cell proteome coverage
Analysis by liquid chromatography and tandem mass spectrometry (LC-MS/MS) can identify and quantify thousands of proteins in microgram-level samples, such as those comprised of thousands of cells. This process, however, remains challenging for smaller samples, such as the proteomes of single mammali...
Autores principales: | Chen, Albert Tian, Franks, Alexander, Slavov, Nikolai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625733/ https://www.ncbi.nlm.nih.gov/pubmed/31260443 http://dx.doi.org/10.1371/journal.pcbi.1007082 |
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