Macaque interferon-induced transmembrane proteins limit replication of SHIV strains in an Envelope-dependent manner

HIV-1 does not persistently infect macaques due in part to restriction by several macaque host factors. This has been partially circumvented by generating chimeric SIV/HIV-1 viruses (SHIVs) that encode SIV antagonist of known restriction factors. However, most SHIVs replicate poorly in macaques unle...

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Detalles Bibliográficos
Autores principales: Sharma, Amit, McLaughlin, Richard N., Basom, Ryan S., Kikawa, Caroline, OhAinle, Molly, Yount, Jacob S., Emerman, Michael, Overbaugh, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625738/
https://www.ncbi.nlm.nih.gov/pubmed/31260493
http://dx.doi.org/10.1371/journal.ppat.1007925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625738/
https://www.ncbi.nlm.nih.gov/pubmed/31260493
http://dx.doi.org/10.1371/journal.ppat.1007925

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